Publications
ORCID: orcid.org/0000-0002-3347-438X
| Authors | Title | Journal | Year | PMID |
|---|---|---|---|---|
| Elham Esmaeilishirazifard, Daniel Guerrero-Romero, Allan J.W. Lui, Abigail Shea, Long V. Nguyen, Maurizio Callari, Riccardo Masina, Kevin Tu, Richard Baird, Paul Edwards, Wendy Greenwood, Steve Fuller, Claire Crafter, Mandy Lawson, Alejandra Bruna, Oscar M. Rueda, Carlos Caldas. | Real-time cell viability monitoring for high-throughput drug screening using tumor xenograft-derived cells | Cell Reports Methods | 2026 | 42202786 |
| Sarah Kronheim, Jiahui Wang, Jiao Yi Chen, Daniel Guerrero-Romero, Suet-Feung Chin, Giulia Lerda, Allan J.W. Lui, Oscar M. Rueda, Federico Gaiti, Carlos Caldas, Long V. Nguyen. | Chemotherapy reshapes cellular clonal landscape via persister programs in breast cancer xenografts | bioRxiv | 2026 | bioRxiv |
| Hee Jin Shin, Sahil Sharma, Sarah Kronheim, May Cheung, Long V. Nguyen. | Protocol to track single-cell-derived clones using DNA barcoding combined with single-cell RNA sequencing | STAR Protocols | 2025 | 4131732 |
| Kevin J Tu, Daniel Guerrero-Romero, Kate Eason, Raquel Manzano Garcia, Jia Wern, Soo-Hwang Teo, Long Nguyen, Stephen-John Sammut, Florian Markowetz, Oscar M Rueda, Carlos Caldas. | The tumor microenvironment of 14,837 breast cancers is associated with clinical outcome independently of genomic subtypes | Cell Reports Medicine | 2025 | 41218603 |
| Long V Nguyen, Yaniv Eyal-Lubling, Daniel Guerrero-Romero, Sarah Kronheim, Suet-Feung Chin, Raquel Manzano Garcia, Stephen-John Sammut, Giulia Lerda, Allan J W Lui, Helen A Bardwell, Wendy Greenwood, Hee Jin Shin, Riccardo Masina, Katarzyna Kania, Alejandra Bruna, Elham Esmaeilishirazifard, Emily A Kolyvas, Samuel Aparicio, Oscar M Rueda, Carlos Caldas | Fitness and transcriptional plasticity of human breast cancer single-cell-derived clones | Cell Reports | 2025 | 40359107 |
| Syed Mohammed Musheer Aalam, Long Viet Nguyen, Megan L Ritting, Nagarajan Kannan | Clonal tracking in cancer and metastasis | Cancer and Metastasis Reviews | 2024 | 37910295 |
| Long V Nguyen and Carlos Caldas. | Functional genomics approaches to improve pre-clinical drug screening and biomarker discovery | EMBO Molecular Medicine | 2021 | 34254730 |
| Long V Nguyen, Karlee Searle, Katarzyna J Jerzak. | Central nervous system-specific efficacy of CDK4/6 inhibitors in randomized controlled trials for metastatic breast cancer | Oncotarget | 2019 | 31695840 |
| Long V Nguyen, Maisam Makarem, Nagarajan Kannan, Annaick Carles, Sneha Balani, Michelle Moksa, Martin Hirst, Connie J Eaves. | Clonal analysis of mouse mammary luminal epithelial cell transplants | Stem Cells and Development | 2019 | 30572802 |
| Xiaoyang Lan, David J. Jorg, Florence MG Cavalli, Laura M Richards, Long V Nguyen, Robert J Vanner, Paul Guilhamon, Lilian Lee, Michelle M Kushida, Davide Pellacani, Nicole I Park, Fiona J Coutinho, Heather Whetstone, Hayden J Selvadurai, Clare Che, Betty Luu, Annaick Carles, Michelle Moksa, Neghmeh Rastegar, Renee Head, Sonam Dolma, Panagiotis Prinos, Michael D Cusimano, Sunit Das, Mark Bernstein, Cheryl H Arrowsmith, Andrew J Mungall, Richard A Moore, Yussanne Ma, Marco Gallo, Mathieu Lupien, Trevor J Pugh, Michael D Taylor, Martin Hirst, Connie J Eaves, Benjamin D Simons, Peter B Dirks. | Fate mapping of glioblastoma reveals an invariant stem cell hierarchy | Nature | 2017 | 28854171 |
| Sneha Balani, Long V Nguyen, Connie J Eaves. | Modeling the process of human tumorigenesis | Nature Communications | 2017 | 28541307 |
| Long V Nguyen, Davide Pellacani, Sylvain Lefort, Nagarajan Kannan, Tomo Osako, Maisam Makarem, Claire L Cox, William Kennedy, Philip Beer, Annaick Carles, Michelle Moksa, Misha Bilenky, Sneha Balani, Sonja Babovic, Ivan Sun, Miriam Rosin, Samuel Aparicio, Martin Hirst, Connie J Eaves. | Barcoding reveals complex clonal dynamics of de novo transformed human mammary cells | Nature | 2015 | 26633636 |
| Peter Eirew, Adi Steif, Jaswinder Khattra, Gavin Ha, Damian Yap, Hossein Farahani, Karen Gelmon, Stephen Chia, Colin Mar, Adrian Wan, Emma Laks, Justina Biele, Karey Shumansky, Jamie Rosner, Andrew McPherson, Cydney Nielsen, Andrew JL Roth, Calvin Lefebvre, Ali Bashashati, Camila de Souza, Celia Siu, Radhouane Aniba, Jazmine Brimhall, Arusha Oloumi, Tomo Osako, Alejandra Bruna, Jose L Sandoval, Teresa Algra, Wendy Greenwood, Kaston Leung, Hongwei Cheng, Hui Xue, Yuzhuo Wang, Dong Lin, Andrew J Mungall, Richard Moore, Yongjun Zhao, Julie Lorette, Long Nguyen, David Huntsman, Connie J Eaves, Carl Hansen, Marco A Marra, Carlos Caldas, Sohrab P Shah, Samuel Aparicio. | Dynamics of genomic clonal evolution in breast cancer patient xenografts at single cell resolution | Nature | 2015 | 25470049 |
| Long V Nguyen, Claire L Cox, Peter Eirew, David JHF Knapp, Davide Pellacani, Nagarajan Kannan, Annaick Carles, Michelle Moksa, Sneha Balani, Sohrab Shah, Martin Hirst, Samuel Aparicio, Connie J Eaves. | DNA barcoding reveals diverse growth kinetics of human breast tumour subclones in serially passaged xenografts | Nature Communications | 2014 | 25532760 |
| Long V Nguyen, Maisam Makarem, Annaick Carles, Michelle Moksa, Nagarajan Kannan, Pawan Pandoh, Peter Eirew, Tomo Osako, Melanie Kardel, Alice MS Cheung, William Kennedy, Kane Tse, Thomas Zeng, Yongjun Zhao, R Keith Humphries, Samuel Aparicio, Connie J Eaves, Martin Hirst. | Clonal analysis via barcoding reveals diverse growth and differentiation of transplanted mouse and human mammary stem cells | Cell Stem Cell | 2014 | 24440600 |
| Nagarajan Kannan, Long V Nguyen, Connie J Eaves. | Integrin ß3 links therapy resistance and cancer stem cell properties | Nature Cell Biology | 2014 | 24914436 |
| Nagarajan Kannan, Long V Nguyen, Maisam Makarem, Yifei Dong, Kingsley Shih, Peter Eirew, Afshin Raouf, Joanne T Emerman, Connie J Eaves. | Glutathione-dependent and -independent oxidative stress-control mechanisms distinguish normal human mammary epithelial cell subsets | PNAS | 2014 | 24821780 |
| Alice MS Cheung, Long V Nguyen, Annaick Carles, Philip Beer, Paul H Miller, David JHF Knapp, Kiran Dhillon, Martin Hirst, Connie J Eaves. | Analysis of the clonal growth and differentiation dynamics of primitive barcoded human cord blood cells in NSG mice | Blood | 2013 | 24030380 |
| Maisam Makarem, Nagarajan Kannan, Long V Nguyen, David JHF Knapp, Sneha Balani, Michael D Prater, John Stingl, Afshin Raouf, Oksana Nemirovsky, Peter Eirew, Connie J Eaves. | Developmental changes in the in vitro activated regenerative activity of primitive mammary epithelial cells | PLoS Biology | 2013 | 23966837 |
| Long V Nguyen, Robert Vanner, Peter Dirks, Connie J Eaves. | Cancer stem cells: an evolving concept | Nature Reviews Cancer | 2012 | 22237392 |
| Mike Berger, Dominick Bosse, M Sara Kuruvilla, Pencilla Lang, Jean-Christophe Murray, Long Viet Nguyen. | Scientific overview: CSCI-CITAC annual general meeting and young investigator’s forum 2010 | Clinical and Investigative Medicine | 2011 | 21463544 |
| Guennadi Kozlov, Marie Menade, Angelika Rosenauer, Long Nguyen, Kalle Gehring. | Molecular determinants of PAM2 recognition by the MLLE domain of poly(A)-binding protein | Journal of Molecular Biology | 2010 | 20096703 |
| Guennadi Kozlov, Long Nguyen, Jessica Pearsall, Kalle Gehring. | The structure of phosphate-bound Escherichia coli adenylosuccinate lyase identifies His171 as a catalytic acid | Acta Crystallographica Section F | 2009 | 19724117 |
| Ni Wang, Lucia Fallavollita, Long Nguyen, Julia Burnier, Moutih Rafei, Jacques Galipeau, Shoshana Yakar, Pnina Brodt. | Autologous bone marrow stromal cells genetically engineered to secrete an igf-I receptor decoy prevent the growth of liver metastases | Molecular Therapy | 2009 | 19367255 |
| Long Nguyen, Guennadi Kozlov, Kalle Gehring. | Structure of Escherichia coli tetrahydrodipicolinate N-succinyltransferase reveals the role of a conserved C-terminal helix in cooperative substrate binding | FEBS Letters | 2008 | 18242192 |
| Guennadi Kozlov, Long Nguyen, Tong Lin, Gregory De Crescenzo, Morag Park, Kalle Gehring. | Structural basis of ubiquitin recognition by the ubiquitin-associated (UBA) domain of the ubiquitin ligase EDD | Journal of Biological Chemistry | 2007 | 17897937 |